A study of the prescribing pattern of antihypertensive drugs in a Tertiary Care Teaching Hospital of Andaman & Nicobar Island
DOI:
https://doi.org/10.7439/ijpr.v7i5.4143
Abstract
Introduction: Hypertension is the increased systolic blood pressure of ?140 mm Hg or diastolic blood pressure of ?90 mm Hg. The antihypertensive drugs currently available are chosen on the basis of their efficacy, side-effects, and cost. Accordingly, a need to survey the pattern of usage of antihypertensive drugs is must, to see if the current usage is rational and in concordance with current guidelines for treatment of hypertension. Therefore this study was carried out with the aim of analyzing the pattern of antihypertensive drugs being prescribed and its adherence with JNC-8 guidelines, in a tertiary care Teaching hospital of Andaman and Nicobar Islands, India. Material and methods: A cross-sectional, observational study was done in ANIIMS, Port Blair, India over a period of 6 months from October 2016 to March 2017, in which analysis of the prescriptions of patients of essential Hypertension was done. A total of 870 prescriptions were analyzed based on age group, gender, number of antihypertensives, combination/ or monotherapy. The results obtained were expressed as percentages and proportion and were compared with JNC-8 Guidelines. Observations: In this study, a total of, 870 prescriptions were analyzed and it was observed that male patients with hypertension were 586(67.3%), and female patients were 284(32.7%), with male: female ratio of 2.05:1. Also most common therapy was the combination therapy in 630(72.4%) patients, out of which a CCB+ Diuretic combination was the commonest in 318(50.4%), followed by ACE-I + Beta Blocker combination in 180(28.6%) patients. Most common Drug used as monotherapy was Diuretics in 110(45.8%) patients, followed by Calcium channel blockers in 82(34.2%) patients, followed by ARBs in 48(20.0%) patients. Conclusion: The trend of hypertension is on the rise, if treated rationally this disease can be overcome. This study suggests the trend of prescribing of antihypertensive drugs in ANIIMS Port Blair, India and will provide a baseline data for similar studies in future.
Downloads
References
. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, et al. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension. 2003; 42(6):1206-52.
. Kochen TA. Hypertensive vascular disease. In: Fauci AS, Braunwal EB, Kasper DL, Hauser SL, Longo DL, Jameson JL, editors. Harrison’s Principles of Internal Medicine. 17th Edition. New York: The McGraw-Hill Companies Inc.; 2008: 1549-62.
. Gupta R. Trends in hypertension epidemiology in India. J Hum Hypertens 2004; 18:73-8.
. Sutters M. Systemic hypertension. In: McPhee SJ, Papadakis MA, Rabow MW, editors. Current Medical diagnosis and treatment. 50th Edition. USA: McGraw Hill Lange; 2011: 416-45.
. Pradeepa R, Mohan V. Hypertension & pre-hypertension in developing countries. Indian J Med Res. 2008; 128:688-90.
. Rang HP, Dale MM, Ritter JM, Flower RJ, editors. The vascular system. In: Rang and Dale’s Pharmacology. 6th Edition. UK: Churchill Livingstone; 2007: 298-320.
. Pai PG, Shenoy J, Sanji N. Prescribing patterns of antihypertensive drugs in a South Indian tertiary care hospital. Drug Invent Today. 2011; 3(4): 38-40.
. Gupta N, Sharma D, Garg SK, Bhargava VK. Auditing of prescriptions to study utilization of antimicrobials in tertiary hospital. Indian J Pharmacol. 1997; 29:411-5.
. Yuen YH, Chang S, Chong CK, Lee SC, Critchlev JA, Chan JC. Drug utilization in a hospital general medical outpatient clinic with particular reference to antihypertensive and antidiabetic drugs. J Clin Pharm Ther. 1998; 23: 287-94.
. Jhaj R, Goel NK, Gautam CS, Hota D, Sangeeta B. Prescribing patterns and cost of antihypertensive drugs in an internal medicine clinic. Ind Heart J. 2001; 53:323-27.
. Mancia G, Grassi G. Antihypertensive treatment: past, present and future. J Hypertens. 1998; 16:1-7.
. Eduardo HV. A Review of the JNC 8 Blood Pressure Guideline, Cardiovascular Disease in Women 2015; 42:3-226-28.
- PDF
Published
How to Cite
Issue
Section
Authors who publish with this journal agree to the following terms:
-
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work’s authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
- Author must Submit Copyright form After acceptance of Article
