DOI:
https://doi.org/10.7439/ijpr.v7i3.4009
Keywords:
Subtractive genomics, Therapeutic drug target, Unique pathways, Homologs
Abstract
Introduction: Antibacterial agents are one of the most frequently used drugs word wide, and contribute immensely to human health system. Maternal health is very important because both fetus and mother are at jeopardy. Many drugs are used in Obstetrics and Gynecology department but they are least studied with respect to drug utilization which is a potential tool in evaluation of health systems. Thus, present study was undertaken to analyze drug utilization pattern of Obstetrics and Gynecology Department in a tertiary care hospital. Methods: This prospective study of the audit prescription was conducted for a period of three months from March 2016 to May 2016 on patients visiting the Obstetrics and Gynecology department during the study period. Patients were enrolled on the basis of inclusion and exclusion criteria. Results 130 patients were analyzed. Antibiotics were prescribed for eclampsia followed by full term pregnancy (FTP) in labor, puerperal sepsis, intra-uterine death with previous LSCS with diabetes and pregnancy induced hypertension. ?-lactams were most commonly prescribed antimicrobials to 47.46% of patients, other drugs that were commonly prescribed were proton-pump inhibitors and NSAIDs. Out of 433 drugs which were prescribed to 130 patients, 316 were antibiotics. The average numbers of antibacterial agents which were prescribed per patients per course was found to be 3.88 and average cost per prescription per day was Rs.210.50 and the average antibiotic cost per encounter was Rs.168.50. Conclusion: Our study demonstrated that most of the prescription were found to be rational according to the use of AMAs which helps in reducing adverse events and health care cost.
Downloads
References
Hawkey PM. The growing burden of antimicrobial resistance. J Antimicrob Chemother. 2008 Sep; 62 Suppl 1:i1-9.
Shankar PR, Partha P, Dubey AK, Mishra P, Deshpande VY. Intensive Care Unit drug utilization in a teaching hospital in Nepal, Kathmandu Univ Med J 2005; 3:130-7.
Walraven G, Zuberi N, Temmerman M. The Silent Burden of Gynecological disease in low income countries. BJOG: International Journal of Obstetrics and Gynaecology. 2005; 112:1177-79.
International Institute for population Sciences (IIPS) and Macro International 2007. National Family Health Survey (NFHS-3), 2005-06: Mumbai India: (I): IIPS.
World Health Organization. Introduction to Drug Utilization Research.[Homepage on the Internet]. 2003. cited 2011 Nov 14 http://www.whocc.no/filearchive/publications/drug_utilization_research.pdf
Shalini S, Murthy NS, Shalini CN, Rajanna MS, Geethamani V. Study of Reproductive tract infections among women attending Urban Health Centres in Banglore City. Indian J Prev. Soc. Med, 2011; 42(3): 267-72.
Baig MS, Bagle TR, Gadappa SN, Deshpande Sonali, Doifode SM. Int J Med Res Health Science. 2013; 2 (2):156-163.
Kaur S, Talwar R. Sabharwal D, Raut DK. Knowledge about transmission dynamics of Sexually transmitted infections. Indian medical Gazette, 2011: 470-75.
Shah BK, Shah VN. Antimicrobial use by the department of obstetrics and gynecology of a tertiary care hospital: Analysis for rationality and other aspects. J Obstet Gynecol Ind 2004; 54:387-92.
Dhaubhadel P, Vaidya A, Chaudhary P. Early detection of precursors of cervical cancer with cervical cytology and visual inspection of cervix with acetic acid. J Nepal Med Assoc. 2008; 47(170):71-76.
Dashputra AV, Badwaik RT. Utilization of analgesics in perioperative cases of teaching hospital. Int J Med Pharm Sci 2013; 3:14-19.
Gyawali S, Shankar PR, Saha A, Mohan L. Study of prescription of injectable drugs and intravenous fluids to inpatients in a teaching hospital in Western Nepal. MJM 2009;12:13-20.
Narwane SP, Patel TC, Shetty YC, Chikhalkar SB. Drug Utilization and Cost Analysis for Common Skin Diseases in Dermatology OPD of an Indian Tertiary Care Hospital-A Prescription Survey. British Journal of Pharmaceutical Research. 2011; 1(1): 9-18.
- PDF
Published
How to Cite
Issue
Section
Authors who publish with this journal agree to the following terms:
-
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work’s authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
- Author must Submit Copyright form After acceptance of Article
