An in-vitro studies on green synthesis of gold nanoparticles against pathogens and cancer cells



  • V. Ramesh

    School of Enzymology and Environmental Toxicology,
    P.G and Research Department of Zoology, Sir Theagaraya College, Chennai-620 021,Tamil Nadu

  • A. Armash

    Department of Microbiology,
    M.I.E.T. Arts and Science College, Tiruchirappalli – 620 007, Tamil Nadu



Metallo-beta lactamase, Pseudomonas


Nanotechnology is a most promising field for generating new applications in medicine. It is imperative to integrate nanoscience and medicine. The present investigation is highly warranted to through more light upon the gold nanoparticles reduced from gold salt through the active principle of medicinal plant. The special emphasis of investigation is the active principle along with gold nanoparticles against for cancer cells. The 70 – 90 nm sized particles were synthesized by using Diospyros ferrea and this confirmed by SEM. These gold nanoparticles showed a characteristic absorption peak at 540 nm in UV spectra. The possibility of protein as a stabilizing material in gold nanoparticles is revealed by FTIR analysis. Remarkably, as a result of wide screening on the application of newly synthesized gold nanoparticles their anticancer potential has been discovered using MTT assay. The antimicrobial activity of AuNPs showed effective against bacteria than the fungal strains.


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How to Cite

Ramesh V, Armash A. . Int J of Pharmc Res [Internet]. 2015Nov.15 [cited 2020Jul.3];5(10):250-6. Available from:


Vol. 5 No. 10 (2015): Oct


Research Articles

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