Bevacizumab (Avastin) for Ocular Disorders

Abnormal ocular neovascularization is major cause of loss of vision.The newly formed vessels are dysfunctional which can leak fluid, cause hemorrhage, or are associated with fibrous proliferation,  resulting in potentially catastrophic loss of vision. Anti VEGF have come as a boon to cure ocular neovascularization. This paper will describe the attempted uses of  bevacizumab , humanized monoclonal antibody to VEGF, for various ocular disorders  and its efficacy in addition to discussing safety. Comments regarding appropriate use of this treatment are based on our current level of knowledge and large ,randomized control studies  are required to expand the use of this wonderful drug.

neovascularization; VEGF; anti VEGF; bevacuzimab