Effects of Sea Salt Based Oral Rinse on Streptococcus Mutans Level and Oral Ecology in Gingivitis Subjects with High Caries Susceptibility: A Randomized Clinical Study



  • Amit M. Mani

    Professor and Head,
    Department of Periodontology,
    Pravara Institute of Medical Sciences, Loni, Maharashtra

  • Shubhangi A Mani

    Department of Orthodontics,
    Pravara Institute of Medical Sciences, Loni, Maharashtra

  • Rajiv Saini

    Consulting Periodontist & Oral Implantologist, Pune




Metformin HCl, Ion-exchange resin, Controlled release


Background: The etiologic role of a pathogenic dental plaque biofilm in the development of gingivitis and dental caries is well documented. This study evaluates the rationale for incorporating sea salt based mouth rinse into a daily oral hygiene regimen along with mechanical plaque control methods on gingival inflammation and caries susceptibility level in mild to moderate gingivitis patients. Methods: A prospective, double-blinded, randomized parallel-group controlled study involving 40subjects was conducted to assess efficacy and safety. Subjects were randomized to receive either the study rinse (H2Ocean)or a water-only preparation. The oral hygiene index (OHI) and S. Mutans Level were measured at baseline and at the end of the study period. Results: Sea salt mouth rinse was significantly better than the control, with respect to both the change in OHI score by 28.89% and S. mutans level by 35%.   No adverse effects were noted in any of the study groups. Conclusion: Sea Salt mouth rinse is a safe and effective treatment for preventing the development of gingival inflammation and S. mutans level in mild to moderate gingivitis population. Further research is needed to evaluate its long-term effects.


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Author Biography

Rajiv Saini, Consulting Periodontist & Oral Implantologist, Pune

Chief, Division of Oral Biosciences



How to Cite

Mani, A. M., Mani, S. A., & Saini, R. (2018). . International Journal of Biomedical and Advance Research, 9(4), 167-170. https://doi.org/10.7439/ijbar.v9i4.4730


Vol. 9 No. 4 (2018): Apr


Original Research Articles

Dr. Jun Ren is a dedicated and experienced registered dietitian and nutritionist who is committed to helping people achieve their health goals through personalized nutrition plans. With a passion for promoting healthy eating habits and preventing chronic diseases, Dr. Ren has been able to assist numerous clients in improving their overall quality of life.

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