Assessment of Serum Minerals and Electrolytes In Thyroid Patients


Methodology

Authors


  • Shailaza Shrestha


    Tutor,
    Department of Biochemistry
    FH Medical College and Hospital,
    Tundla, UP

  • Arvind Bharti


    Assistant Professor,
    Department of Biochemistry
    FH Medical College and Hospital, Tundla, UP

  • Rahul Rai


    Tutor,
    Department of Anatomy
    KD Medical College and Hospital, Mathura, UP

  • Mukesh Singh


    Department of Microbiology
    Teerthanker Mahaveer Medical College and Research Center, Moradabad, UP

DOI:



https://doi.org/10.7439/ijasr.v1i6.2189

Keywords:


Subclinical hypothyroidism, hypothyroidism, subclinical hyperthyroidism, hyperthyroidism

Abstract

Introduction: The effect on thyroid hormones on electrolytes and minerals has not been well established and the underlying mechanisms are not well understood. Only few data on the association between thyroid function and electrolyte disorders exists. Thus our aim was to assess the levels of serum electrolytes and minerals in the patients with thyroid disorders.
Materials and methods:   75 patients and 30 controls were included. Thyroid hormones (T3, T4, TSH) were measured by vidas autoanalyser. Serum calcium, phosphorous and magnesium were estimated by kit based method using semiautoanalyser. Serum sodium, potassium and chlorides were estimated using ion selective electrodes. Statistical analysis was done using SPSS 16.
Results: Patients with subclinical hypothyroidism and overt hypothyroidism showed significant decrease in serum calcium and sodium levels and significant increase in serum phosphorous, magnesium, potassium and chloride levels (p 0.05). In case of subclinical hyperthyroidism significant difference could not be obtained among controls and patients (p>0.05). However for overt hyperthyroid patients, serum phosphorous was significantly decreased and serum sodium was increased significantly (p 0.05). Rest of the results were non significant. When correlated with TSH, serum calcium and sodium showed negative correlation whereas it was positive for serum phosphorous, magnesium, potassium and chloride in case of hypothyroidism. For hyperthyroid patients, correlation was negative for magnesium and chloride whereas positive for the rest parameters. But none of correlations were statistically significant (p>0.05).
Conclusion: Thyroid patients should be regularly checked for serum electrolytes. Early detection and treatment can prevent the further complications and will be helpful during the management of thyroid patients.

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Published

2015-07-30

How to Cite

1.
Shrestha S, Bharti A, Rai R, Singh M. . Int J of Adv in Sci Res [Internet]. 2015 Jul. 30 [cited 2022 Oct. 6];1(6):259-63. Available from: http://ssjournals.org/index.php/ijasr/article/view/2189

Issue

Vol. 1 No. 6 (2015): IJASR

Section

Research Articles

Dr. Jun Ren is a dedicated and experienced registered dietitian and nutritionist who is committed to helping people achieve their health goals through personalized nutrition plans. With a passion for promoting healthy eating habits and preventing chronic diseases, Dr. Ren has been able to assist numerous clients in improving their overall quality of life.

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