Journals

Synthesis and Molecular Docking studies of Heterocyclic Chalcone Derivatives as BRCA1 inhibitors

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Authors Yaseen Mowlana Research Scholar, PG & Research Department of Chemistry, Jamal Mohamed College, Trichy-20 A. Jamal Abdul Nasser Department of Chemistry, Jamal Mohamed College, Tiruchirappalli – 620 020, Tamilnadu DOI: https://doi.org/10.7439/ijpc.v5i6.2110 Abstract According to Claisen-Schmidt condensation a series of novel substituted Indolyl Chalcone derivatives were synthesized and evaluated Docking study. The synthesized compounds have … Read more

Effects of mono and dinuclear copper(II) complexes derived from non-steroidal anti-inflammatory drug naproxen on human serum paraoxanase1 (PON1) activity

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Esra Dilek, Sema Caglar   Abstract   The inhibition of human paraoxonase 1 (PON1, EC 3.1.8.1) enzyme, with two Cu(II) complexes derived from naproxen was investigated by using the paraoxonase activity method with diethyl 4-nitrophenyl phosphate as substrate. The complexes [Cu2(µ-nap)4(3-pic)2] (1) and [Cu(nap)2(H2O)(4-pic)2] (2) decreased the in vitro PON1 activity with different inhibition mechanisms. … Read more

Antioxidant Activity of Ethanolic Extracts of Callicarpa Linata Leaf

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Authors Qadrie ZL PRIST UNIVERSITY, Centre for Research and Development, Vallam, Thanjavur, TN Rajkapoor B. Department of Pharmacology, Faculty of Medicine, Sebha University, Sebha Kavimani S College of Pharmacy, Mother Theresa Post Graduate and Research Institute of Health Science, Pondicherry, TN DOI: https://doi.org/10.7439/ijpr.v5i6.2095 Abstract Antioxidants are our first line of defense against free radical damage, … Read more

Isolation and characterization of acid and base degradation products in Atenolol and Hydrochlorothiazide and a validated selective stability-indicating HPLCUV method for their quantification

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Authors Indrani Bhattacharyya Dr B.C Roy College of Pharmacy and AHS, Dr. Meghnad Saha Sarani, Bidhan Nagar Pin-713206, Durgapur, West Bengal, Souvik Basak Dr B.C Roy College of Pharmacy and AHS, Dr. Meghnad Saha Sarani, Bidhan Nagar Pin-713206, Durgapur, West Bengal, Arindam Maity Dr B.C Roy College of Pharmacy and AHS, Dr. Meghnad Saha Sarani, … Read more

Simultaneous determination of Cefixime trihydrate and Ofloxacin in pharmaceutical dosage form by second order derivative UV spectrophotometry

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Audumbar Digambar Mali, Ritesh Bathe, Ashpak Tamboli   Abstract    Derivative spectrophotometry offers a useful approach for the analysis of drugs in multi-component formulation. In this study a second order derivative spectrophotometric method is applied for the simultaneous determination of Cefixime Trihydrate and Ofloxacin in Tablet dosage form. The measurements were carried out at wavelengths … Read more

Knowledge of epilepsy among IInd year students of medical fraternity

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Sudarshan Surendran, Maheswaran S, James Gonsalves, Prima J.J. D’Souza, Keerthana Balaji   Abstract   Objectives: To test the awareness and knowledge regarding epilepsy among II year medical students. Materials and methods: A questionnaire designed to test the knowledge levels of students regarding epilepsy was chosen and administered to students for collecting their responses. The questionnaire … Read more

Anticonvulsant activity of Granisetron in Albino mice

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Authors Sathisha Aithal S.S. Institute of Medical Sciences and research centre, Davangere Balaji V Post graduate, Department of Pharmacology, S.S. Institute of Medical Sciences and Research Centre, Davangere. Geetha S Post graduate, Department of Pharmacology, S.S. Institute of Medical Sciences and Research Centre, Davangere. Swetha ES Post graduate, Department of Pharmacology, S.S. Institute of Medical … Read more

Design, synthesis and evaluation of acute toxicity studies and anti-depressant activities of some new derivatives of 1, 3-benzoxazin- 4-one

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Authors Nachiket Dighe Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Loni, MS 413736 Pankaj S. Shinde Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Loni, MS, -413736. Ravindra B. Lawre Department of Pharmaceutics, Pravara Rural College of Pharmacy, Loni, MS, -413736. Santosh B. Dighe Department of Pharmacology, Pravara Rural College of Pharmacy, … Read more

Assessment of cardiovascular fitness [VO2 max] among medical students by Queens College step test

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Authors Tauseef Nabi Khushoo Department of Medicine, MMIMSR, Mullana, Ambala, Nadeema Rafiq Department of Physiology, MMIMSR, Mullana, Ambala Ouber Qayoom Department of Medicine, MMIMSR, Mullana, Ambala, DOI: https://doi.org/10.7439/ijbar.v6i5.1965 Keywords: CAD Abstract Objective: Cardio respiratory fitness in terms of maximum oxygen uptake [VO2max] reflects physical fitness of a person.VO2max is single best measure of cardio respiratory … Read more