Electrochemical Investigation of Uric acid at Poly (Isoniazid) film Modified Carbon paste Electrode


Methodology

Mamatha G. P, Deepak M P, Sherigara B S

 

Abstract

 

A voltammetric determination of Uric acid (UA) has been studied on electropolymerisation of Isoniazid     modified carbon paste electrode. Voltammetric behavior of Uric acid (UA) on the poly (Isoniazid) modified carbon paste electrode was investigated with electrochemical parameters of cyclic voltammetry. The variation of P,Scan rate, Concentration of Uric acid (UA) has been studied. In optimal conditions, the oxidation peak current of UA on the poly (Isoniazid) modified carbon paste electrode was enhanced greatly indicating high sensitivity. The low detection limit (LOD) and low detection quantity (LOQ) of UA has been found to be 1.173 µM and 3.910 µM with a correlation coefficient of 0.99442. The practical application of the modified electrode in the determination of UA has good selectivity and high sensitivity.

 

Keywords

 

Isoniazid, Uric acid, Electropolymerization, Carbon paste electrode, Cyclic Voltammetry

 

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DOI: http://dx.doi.org/10.7439/ijpc.v4i4.92

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Copyright (c) 2014 International Journal of Pharmaceutical Chemistry

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