A study Antiurolithiatic Activity of ethanolic extract of Asparagus racemosus in animal models

Authors

Jagannath N

SVS Medical College, Mehabubnagar
Asha P Dass

KBNIMS, Gulbarga
Khasif Ahmed

KBNIMS, Gulbarga

DOI:

https://doi.org/10.7439/ijpr.v5i11.2530

Abstract

Objective: To investigate the Antiurolithiatic Activity of ethanolic extract of Asparagus racemosus in animal models. Materials and Methods: The study includes performing on healthy albino rats of either sex weighing 220 270gms and urolithiasis was induced by oral administration of ethylene glycol and ammonium chloride water. The parameters studied are serum analysis for Urea, Creatinine, Calcium and Phosphorus, Body Weight of animals included in the study group and Histopathological Study of kidney for the presences crystals. Results In our study the Ethanolic extract of Asparagus Racemosus with doses of 800mg/kg and 1600mg/kg per orally to rats showed significant reduction in serum urea, creatinine, calcium and phosphorus levels in urolithiatic rats when compared to the positive control rats (Group II). These results were found to be statistically significant (p 0.05). Conclusion: Ethanol Extract of Asparagus racemosus has a significant antiurolithiatic activity.

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Author Biography

Khasif Ahmed, KBNIMS, Gulbarga

Dept. of Pharmacology

Published

2015-12-15

How to Cite

N J, Dass AP, Ahmed K. . Int J of Pharmc Res [Internet]. 2015Dec.15 [cited 2020Jul.3];5(11):316-9. Available from: https://ssjournals.net/index.php/ijpr/article/view/2530

Issue

Vol. 5 No. 11 (2015): Nov

Section

Research Articles

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